NOW Foods Supplements, SAMe (S-Adenosyl-L-Methionine)200 mg, Nervous System Support*, 60 Veg Capsules

I was able to view lab test for quality on this product. I have decided I will only buy NOW because I trust the lab test they publish is true. The also show a group of competitions products and how they rate, plus Consumer Labs says they thing NOW brand is quality. This is a big issue for me. Sam-e helps me with energy. I like it. Great value. This is an update as my first attempted was ???

Day 20 review. I rarely write reviews for products but I’m amazed at how well this stuff works. The pandemic has had an impact on my mental health and it finally reached a point where I was seeking out help. I have taken ssri’s in the past and they do work but I found the side effects to be a bit much. I have taken Sam-e in the past but never had much success but after some additional research I figured I’d give it another go. Consistency is key to knowing if this will work for you or not. Take it at the same time daily for a couple weeks and make sure your getting 7+ hours of sleep at night.**A word of caution to anyone who’s currently taking ssri’s, microdosing psychedelics or recreationally taking drugs that affect serotonin. Sam-e is known to work on serotonin in the body, mixing these drugs with Sam-e can be dangerous and can potentially cause serotonin syndrome. Talk to your doctor first and/or stop taking the other drugs well before trying Sam-e. **I take only 200mg of sam-e first thing in the morning on an empty stomach with some caffeine (200mg rapid release + 100mg extended release) and a 21 mg nicotine patch (New Years resolution to quit vaping). I don’t eat for the next 30 minutes to an hour. I store Sam-e in the fridge and take it with water.It has a subtle effect to it that is recognizable to people who have taken drugs that affect serotonin. There is some stomach discomfort but that’s to be expected and not as bad as some make it out to be (mine might be caused my the caffeine on an empty stomach and your stomach also has many serotonin receptors). The most noticeable difference has been my quality of sleep, it’s improved dramatically. My depression and anxiety have also improved to a manageable level. I work a physically job and have noticed some pain relief in my joints. It’s been an overall positive experience.It’s important to keep your expectations reasonable. It’s not a magic pill that will make you super happy but it can give you some control back of your negative emotions. You’ll still have bad days but they won’t be quite as bad. This is my experience so far, your mileage may vary. Some people might need 400mg but I would try just 200mg first and see how it goes. It’s important to keep your dosing consistent and also the way you dose (not eating with the food). I refrigerate mine because I read that it was recommended to prevent oxidation of the drug (not sure if it’s true or not but it can’t hurt).Overall I look forward to taking Sam-e in the morning. It’s helped me significantly. This is the brand I’ve taken. The capsules have no flavor and might be “large” for some but I have never had an issue taking them. If your curious about the effectiveness of Sam-e, check out pubmed to get some unbiased research. Good luck!

Takes the edge of a bit and boosts mood. I notice I have to go pee more often as a side effect.

Good product but expensive.

Excellent product. Cheaper than the dog SAM-e pills and just as effective. More economical to purchase giving you more for the price than the veterinary formula.

Read the other reviews. There were unstable BAD capsules in the bottle. I took 4 and didn’t realize they were bad. I suffered HORRIFIC side effects for a week. Passing out, nausea, severe headache, severe fatigue and mental issues (anxiety and crying). The inside looked like a separate capsule that is rubbery like playdoh. They smelled awful and tasted horrible. I am so glad I figured it out before I took more.

Doesn't work for me. 5-htp is better for me. Everybody is different

Just started taking. Too early to review the affects. However it came fast and is fresh. Label says put in the fridge so I did that after opening. So far it’s my 2nd day of taking just 1 pill.Update March 8 2024: Just order 2nd bottle. My mood has been pretty stable. While not overly happy, I do feel good. Sleep seems to have gotten better since my last update. I also been taking a B complex consistently with it so energy is great. I’m usually thinking negative but, not much any more. Thoughts aren’t racing as much and less ruminating so that’s a bigger plus for me.Update: Honestly idk if they’re working or not. I feel as good as I did before taking them when I was taking 5HTP. My sleep is still the same, no improvement. If this supposed to help with social anxiety and motivation, I see no improvement in those areas either. Pain, I’m not usually in pain so idk.I started with 200mg and have increased up to 600mg. Nothing really noticeable. Maybe the only benefit is energy? I noticed an improvement in that area, but idk if it’s contributed to this or the B-complex I’ve been taking with it.I think im gonna up the dose to 800mg as that’s about the safest dose to take up to. Imma have to buy a new bottle soon to complete that, but I’ll probably get the 400mg caps.Side note: Caps are still white and not changing color as some stated. Probably due to following instructions and keeping them in the fridge.